There currently are a variety of options to travel by night bus or night train from Frankfurt am Main (Germany) to Prague (Czech Republic), taking between approximately 6 and 10 hours: Namely the BUS Amsterdam - Praha and the EN 40459. These lines are operated by Regiojet and ÖBB.

Next offers

Regiojet operates both night trains and night buses across Europe, providing various travel options. Their night trains feature several types of cabins, including seats that can recline slightly for added comfort, as well as private sleeping couchettes that accommodate one to four passengers, equipped with bedding and duvets. Wifi is available and breakfast and coffee are complimentary. Regiojet night buses feature ergonomic seating that can recline for comfort, with generous legroom and amenities such as USB charging ports, free WiFi, personal entertainment screens, and complimentary refreshments available during the journey. There is also a toilet on the bus.

The Austrian Federal Railways (ÖBB) operate the Nightjet and Euronight trains (the latter together with other national railway agencies). The ÖBB usually offer three types of carriages in their night trains: seats, couchettes, and sleepers. While seats are only for the bravest, couchettes and sleepers offer a more comfortable journey. Couchettes accommodate up to six people, while sleepers are private compartments for one to three people. They sometimes include a private bathroom or even a shower, sometimes only a sink.

For the next 7 dates with connections, the cheapest offer starts at 26 EUR. Check our connection pages below for all availabilities!

Offers on the date of your choice

Next available offers

Sat, 31.05.2025

from 35 EUR

Sun, 01.06.2025

from 40 EUR

Mon, 02.06.2025

from 30 EUR

Tue, 03.06.2025

from 26 EUR

Wed, 04.06.2025

from 26 EUR

Thu, 05.06.2025

from 26 EUR

Fri, 06.06.2025

from 35 EUR