There currently is one option to travel by night bus from Rome (Italy) to Prague (Czech Republic), taking approximately 20 hours: Namely the BUS Řím - Praha operated by Regiojet.

Next offers

Regiojet operates both night trains and night buses across Europe, providing various travel options. Their night trains feature several types of cabins, including seats that can recline slightly for added comfort, as well as private sleeping couchettes that accommodate one to four passengers, equipped with bedding and duvets. Wifi is available and breakfast and coffee are complimentary. The night buses are designed with comfortable, spacious seats that recline, providing ample legroom. Each bus is equipped with individual power outlets, free hot drings, free WiFi, and onboard entertainment systems to enhance the travel experience. Buses also feature a toilet.

For the next 7 dates with connections, the cheapest offer starts at 1249 CZK. Check our connection pages below for all availabilities!

Offers on the date of your choice

Next available offers

Wed, 26.03.2025

from 1399 CZK

Wed, 02.04.2025

from 1249 CZK

Wed, 09.04.2025

from 1249 CZK

Wed, 16.04.2025

from 1599 CZK

Sun, 20.04.2025

from 1599 CZK

Wed, 23.04.2025

from 1399 CZK

Sun, 27.04.2025

offers