There currently are a variety of options to travel by night train from Zurich to Prague, taking approximately 13 hours: Namely the EN 40459, and the EC 459. These lines are operated by ÖBB, and DB.
The Austrian Federal Railways (ÖBB) operate the Nightjet and Euronight trains (the latter together with other national railway agencies). ÖBB night trains typically feature three types of carriages: seats, couchettes, and sleepers. Seats are for the bravest, while couchettes and sleepers provide a more comfortable journey. Couchettes can hold up to six people, whereas sleepers are private compartments for one to three people. They sometimes include a private bathroom or even a shower, sometimes only a sink.
Deutsche Bahn (DB) exited the actual night train business in 2016. However, it operates around a dozen Intercity and Eurocity trains that run exclusively at night. These trains only have first and second class seats. The cars remain lit throughout the night and the seats cannot be reclined.
For the next 7 dates with connections, the cheapest offer starts at 141 CHF. Check our connection pages below for all availabilities!